Diagnostic utility of new immunoassays for the cardiac markers cTnI, myoglobin and CK-MB mass |
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Authors: | Weber Michael Rau Matthias Madlener Katharina Elsaesser Albrecht Bankovic Dragic Mitrovic Veselin Hamm Christian |
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Affiliation: | Kerckhoff Heart Center, Department of Cardiology, Bad Nauheim, Germany. M.Weber@kerckhoff-klinik.de |
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Abstract: | OBJECTIVES: We investigated the diagnostic value of a new system, the Innotrac Aio! immunoassays for troponin, myoglobin and CK-MB, in 270 samples from patients with ACS, after bypass surgery (CABG) or with stable heart failure in comparison to the respective Roche assays. RESULTS: The values of the cardiac markers assessed by the respective assays correlated (cTnT/cTnI Rho = 0.94, myoglobin Rho = 0.87, CK-MB Rho = 0.84). If values were dichotomised, we found a high concordance of test positive and negative classified patients by troponins with the respective assays. CONCLUSION: There is strong evidence that the Innotrac Aio! system for cTnI measurement can be used reliably. |
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Keywords: | Cardiac markers Troponin Myoglobin CK-MB Acute coronary syndromes |
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