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Diagnostic utility of new immunoassays for the cardiac markers cTnI, myoglobin and CK-MB mass
Authors:Weber Michael  Rau Matthias  Madlener Katharina  Elsaesser Albrecht  Bankovic Dragic  Mitrovic Veselin  Hamm Christian
Affiliation:Kerckhoff Heart Center, Department of Cardiology, Bad Nauheim, Germany. M.Weber@kerckhoff-klinik.de
Abstract:OBJECTIVES: We investigated the diagnostic value of a new system, the Innotrac Aio! immunoassays for troponin, myoglobin and CK-MB, in 270 samples from patients with ACS, after bypass surgery (CABG) or with stable heart failure in comparison to the respective Roche assays. RESULTS: The values of the cardiac markers assessed by the respective assays correlated (cTnT/cTnI Rho = 0.94, myoglobin Rho = 0.87, CK-MB Rho = 0.84). If values were dichotomised, we found a high concordance of test positive and negative classified patients by troponins with the respective assays. CONCLUSION: There is strong evidence that the Innotrac Aio! system for cTnI measurement can be used reliably.
Keywords:Cardiac markers   Troponin   Myoglobin   CK-MB   Acute coronary syndromes
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