| CYFRA21-1、CA724、AFP联合检测对原发性肝癌的诊断价值 |
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| 引用本文： | 赵惠柳,黄昭东,刘志民,雷考宁,黄金莲. CYFRA21-1、CA724、AFP联合检测对原发性肝癌的诊断价值[J]. 标记免疫分析与临床, 2009, 16(1): 6-8 |
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| 作者姓名： | 赵惠柳 黄昭东 刘志民 雷考宁 黄金莲 |
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| 作者单位： | 广西医科大学附属肿瘤医院检验科,广西,南宁,530021 |
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| 摘 要： | 探讨血清CYFRA21-1、CA724、AFP联合检测对原发性肝癌（PHC）的诊断价值。选取PHC患者65例、肝硬化患者47例、正常对照组40名，应用电化学发光免疫分析技术检测其血清CYFRA21—1、CA724、AFP水平。结果表明：PHC患者血清AFP、CYFRA21—1、CA724阳性率分别为72．3％、44．6％、35．4％；AFP、CYFRA21-1和CA724三项联合检测阳性率有显著提高，达95．4％，与单-AFP阳性率相比有显著性差异（P〈0．05），而特异性无明显下降（P〉0．05）。AFP、CY-FRA21-1和CA724联合检测对原发性肝癌的诊断具有良好的临床应用价值。
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| 关 键 词： | 原发性肝癌 细胞角质蛋白19片段 糖类抗原724 甲胎蛋白 联合检测 |
Clinical Value of Combined Detection of Serum CYFRA21-1,CA724 and AFP Levels in Patients with Primary Hepatic Carcinoma |
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| ZHAO Hui-liu,HUANG Zhao-dong,LIU Zhi-min,LEI Kao-ning,HUANG Jin-lian. Clinical Value of Combined Detection of Serum CYFRA21-1,CA724 and AFP Levels in Patients with Primary Hepatic Carcinoma[J]. Labeled Immunoassays and Clinical Medicine, 2009, 16(1): 6-8 |
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| Authors: | ZHAO Hui-liu HUANG Zhao-dong LIU Zhi-min LEI Kao-ning HUANG Jin-lian |
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| Affiliation: | ZHAO Hui-liu,HUANG Zhao-dong,LIU Zhi-min,LEI Kao-ning,HUANG Jin-lian(Department of clinical laboratory,The Affiliated Cancer Hospital of Guangxi Medical University,Nanning 530021,China) |
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| Abstract: | To explore the clinical value of combined test of serum CYFRA21-1, CA724 and AFP levels in the diagnosis of patients with primary hepatic carcinoma (PHC). The serum CYFRA21-1, CA724 and AFP levels in 65 patients with primary hepatic carcinoma, 47 patients with cirrhosis, and 40 normal controls were measured by electrochemiluminescence immunoassay. The results showed that the positive rates of serum AFP, CYFRA21-1 and CA724 in patients with PHC were 72.3%, 44.6% and 35.4% separately. The positive rate of com... |
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| Keywords: | Primary hepatic carcinoma CYFRA21-1 CA724 AFP Combined detection |
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