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人 BMP2和 OPG共表达真核载体的构建与骨质疏松基因治疗相关性的研究
引用本文:TAO Hui-ren,CHEN Su-min,JI Zong-ling,HU Yun-yu,LIU Ji-zhong,陶惠人,陈苏民,纪宗玲,胡蕴玉,刘继中.人 BMP2和 OPG共表达真核载体的构建与骨质疏松基因治疗相关性的研究[J].中国组织工程研究与临床康复,2002,6(20):3130-3131.
作者姓名:TAO Hui-ren  CHEN Su-min  JI Zong-ling  HU Yun-yu  LIU Ji-zhong  陶惠人  陈苏民  纪宗玲  胡蕴玉  刘继中
作者单位:1.Institute of Orthopedic Surgery,Xi jing Hospital,Xi ' an 710032,China;2.Department of Bi ochemistry Molecular Biology,Four th Mili-tary Medical University,Xi ' an 710032,China
摘    要:Boneisadynamictissue,thelevelofbonemassreflectsthebalanceofboneformationandresorption,whichinvolvesthecoor-dinateregulationofbone-formingcells(osteoblasts)andbone-resorbingcell(osteoclasts).Avarietyoflocalgrowthfactorsandcytokinesaswellassystemicpeptideandsteroidhormonesregulatethedifferentiationofimmatureprecursorcellsandtheactivityofmaturecellsinboththeosteoblasticandtheosteoclasticlineage,suchasbonemorphogeneticprotein-2(BMP-2)andosteoprotegenin(OPG)犤1犦.Inaddition,…

文章编号:1671-5926(2002)20-3130-02
修稿时间:2002年1月23日

Studies on coexpression of human BMP-2 and OPG and the feasibility of gene treatment for osteoporosis
TAO Hui-ren,CHEN Su-min,JI Zong-ling,HU Yun-yu,LIU Ji-zhong.Studies on coexpression of human BMP-2 and OPG and the feasibility of gene treatment for osteoporosis[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2002,6(20):3130-3131.
Authors:TAO Hui-ren  CHEN Su-min  JI Zong-ling  HU Yun-yu  LIU Ji-zhong
Abstract:
Keywords:bone morphogenetic protein-2  oste oprotegerin  gene expression  
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