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Effects of Shenmai Injection on Blood SOD Activity and MDA Level in Senile Patients with Coronary Heart Disease
作者姓名:苏显明  马奕  黄若文  王晓虹  王永兴
作者单位:Geriatric and Cardiovascular Department First Hospital of Xi'an Jiaotong University,Xi'an 710061,China,Geriatric and Cardiovascular Department,First Hospital of Xi'an Jiaotong University,Xi'an 710061,China,Geriatric and Cardiovascular Department,First Hospital of Xi'an Jiaotong University,Xi'an 710061,China,Geriatric and Cardiovascular Department,First Hospital of Xi'an Jiaotong University,Xi'an 710061,China,Geriatric and Cardiovascular Department,First Hospital of Xi'an Jiaotong University,Xi'an 710061,China
摘    要:In order to approach the effects of Shenmai Injection on SOD activity and MDA level in the senilepatients with coronary heart disease,48 cases,who had stenosis of over 70% in more than one branchesof the coronary arteries,were assigned randomly into a treatment group (given Shenmai Injection plusthe routine treatment) and a control group (given the routine treatment only).The superoxide dismutase(SOD) activity and malondialdehyde (MDA) level were determined before treatment and at the end of a3-week treatment.The results showed that in the treatment group,the SOD activity was significantlyincreased (P<0.05) and the MDA level markedly decreased (P<0.01) in the treatment group.It can beconcluded that Shenmai Injection may enhance the antioxidant ability of the senile patients withcoronary heart disease.

关 键 词:冠心病  老年  参麦注射剂  中药制剂  抗氧化酶  酶活性

Effects of Shenmai Injection on Blood SOD Activity and MDA Level in Senile Patients with Coronary Heart Disease
Xianming Su,Yi Ma,Ruowen Huang,Xiaohong Wang,Yongxing Wang.Effects of Shenmai Injection on Blood SOD Activity and MDA Level in Senile Patients with Coronary Heart Disease[J].Journal of Traditional Chinese Medicine,2005,25(1):50-53.
Authors:Xianming Su  Yi Ma  Ruowen Huang  Xiaohong Wang  Yongxing Wang
Institution:Geriatric and Cardiovascular Department, First Hospital of Xi'an Jiaotong University, Xi'an 710061, China.
Abstract:In order to approach the effects of Shenmai Injection on SOD activity and MDA level in the senile patients with coronary heart disease, 48 cases, who had stenosis of over 70% in more than one branches of the coronary arteries, were assigned randomly into a treatment group (given Shenmai Injection plus the routine treatment) and a control group (given the routine treatment only). The superoxide dismutase (SOD) activity and malondialdehyde (MDA) level were determined before treatment and at the end of a 3-week treatment. The results showed that in the treatment group, the SOD activity was significantly increased (P<0.05) and the MDA level markedly decreased (P<0.01) in the treatment group. It can be concluded that Shenmai Injection may enhance the antioxidant ability of the senile patients with coronary heart disease.
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