Theory-based research in schizophrenia

TOPIC: Theoretical models to guide research into schizophrenia. PURPOSE: To review the most commonly used biological and environmental models of schizophrenia. SOURCES: Published literature and research conducted by the author. CONCLUSIONS: The vulnerability model includes both biological and environmental variables that impact the course of schizophrenia and treatment. RESPONSES: Thus, it may be a useful framework for nursing research examining responses to various psychosocial treatments in schizophrenia.