重症支气管哮喘无创正压通气的疗效评价

目的：无创通气在重症支气管哮喘患者的疗效评价。方法：观察20例应用无创通气治疗重症哮喘患者治疗前，治疗后4h，24h及72h的血气指标及部分生理指标变化；治疗前后肺功能PEF，FEV1％的变化。与20例使用常规方法治疗的重症哮喘患者作了对比。结果：无创通气组的血气指标（pH，PaO2，PaCO2），肺功能指标（呼吸频率，PEF，FEV1％）以及心率的改善均优于治疗前及对照组（P〈0．05）。结论：应用无创正压通气治疗危重症哮喘效果好，并发症少，患者易于接受，值得临床推广。

Evaluation of Noninvasive Ventilation in Treatment of Patients with Severe Asthma

Objective: To evaluate the effectiveness of noninvasive ventilation in patients with severe asthma. Methods:40 cases with severe asthma patients were assigned into two groups:the BiPAP group and the conventional group. Change of pH, PaCO2,PaO2, RR and HR were measured before the treatment and 4 hours,24huors,72hours after the treatment, and the comparison was made between the two groups. Results:Significant differences were found in the BiPAP group in the improvement of pH and PaO2, PEF and FEV1 % and decreased value of PaCO2 ,HR, RR before and after the treatment , compared with the conventional group(P<0. 05). Conclusion: The noninvasive ventilation in treating severe asthma is effective, well-compliant and has few complication.