| 氟对大鼠抗氧化酶系统的影响及“抗氟灵”的拮抗作用研究 |
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| 引用本文： | 刘建东,杨少杰.氟对大鼠抗氧化酶系统的影响及“抗氟灵”的拮抗作用研究[J].工业卫生与职业病,1996,22(3):149-151. |
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| 作者姓名： | 刘建东 杨少杰 |
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| 作者单位： | [1]同济医科大学职业医学研究所 [2]湖北省劳动厅职业卫生与安全处 |
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| 基金项目： | 中国有色金属总公司“八·五”项目,冶金工业部资助基金 |
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| 摘 要： | 选健康雄性Ｗｉｓｔａｒ大鼠４０只,随机分为５组,Ａ组为对照组饮自来水,Ｂ,Ｄ,Ｅ组饮１８０ｍｇＦ／Ｌ溶液,Ｃ组饮相同氟浓度＋２４ｇ％“抗氟灵”混合液。为期２个月,处死Ａ,Ｂ,Ｃ三组,检测相应指标;Ｄ组改饮自来水,Ｅ组改饮２４ｇ％“抗氟灵”,继续观察１个半月,处死,检测相应指标。
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| 关 键 词： | 氟 抗氟灵 超氧化物歧化酶 拮抗作用 |
STUDY ON EFFECT OF FLUORIDE ON ANTI-OXIDASE SYSTEM IN RATS AND ANTAGONISM TO FLUORIDE BY"KANGFULING |
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| Liu Jiandong et al.STUDY ON EFFECT OF FLUORIDE ON ANTI-OXIDASE SYSTEM IN RATS AND ANTAGONISM TO FLUORIDE BY"KANGFULING[J].Industrial Health and Occupational Diseases,1996,22(3):149-151. |
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| Authors: | Liu Jiandong |
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| Abstract: | To observe the effect of fluoride on the activities of SOD and GSH-Px and the content of MDA in blood and the antagonism to fluoride by "Kangfuling ",40 healthy Wistar rats were randomly divided into five groups, respectively administrated fluoride solution and "Kangfuling". The experiment results revealed that fluoride could inhibit the activities of SOD and GSH-Px and increase the content of MDA,while "Kangfuling"could resist the inhibition and revive the activities of SOD and GSH-Px which has been reduced by fiuoride. |
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| Keywords: | Fluoride "Kangfuling" SOD GSH-Px MDA |
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