| 催眠药的药物相互作用 |
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| 引用本文： | 喻东山. 催眠药的药物相互作用[J]. 国外医学:老年医学分册, 2011, 32(3): 127-131 |
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| 作者姓名： | 喻东山 |
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| 作者单位： | 南京医科大学附属脑科医院,南京,210029,中国 |
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| 摘 要： | 大部分催眠药（如阿普唑仑、地西泮、咪达唑仑、三唑仑、氯硝西泮、唑吡坦和佐匹克隆）主要经3A4酶代谢，理论上讲，抑制3A4酶的药物增加这些催眠药的血药浓度，而诱导3A4酶的药物则降低这些催眠药的血药浓度。
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| 关 键 词： | 苯二氮革类药物 Z-字催眠药 药物相互作用 |
Hypnotic Drug Interactions |
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| Yu Dongshan. Hypnotic Drug Interactions[J]. Foreign Medical Sciences(Geriatrics), 2011, 32(3): 127-131 |
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| Authors: | Yu Dongshan |
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| Affiliation: | Yu Dongshan (Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing 210029, China) |
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| Abstract: | Hypnotics （such as Alprazolam, Diazepam, Midazolam, Triazolam, Clonazepan, Zolpidem and Zopiclone） are metabolized by chromosome c P450 3A4 enzyme. Theoretically the plasma levels of these hypnotics can be increased by some drugs inhibiting P450 3A4 enzyme and can be decreased by some drugs inducing P450 3A4 enzyme. |
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| Keywords: | Benzodiazepines Z - Hypnotics Drug Interaction |
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