2004～2005年我院抗抑郁药的应用分析

目的：了解我院抗抑郁药的应用现状和发展趋势。方法：对2004—2005年我院抗抑郁药的种类、用量、金额、用药频度等进行回顾性分析。结果：抗抑郁药的销售金额和用药频度呈上升趋势，分别增长24．76％和23．21％：购药金额前3位依次为：SSRIs、其他类和SNRIs，用药频度前3住依次为SSRIs、其他类和TCA。用药频度居前的药物有氟哌噻吨／关利曲辛、氟西汀和阿米替林等。日均用药金额介于0．55～16．08元，购药金额与DDDs序号比在0.67～2．67之间；进口品种用药金额比例大；用药量随季节有所波动。结论：新型抗抑郁药的应用占主导地位并呈上升趋势，TCA对抗抑郁的作用仍不容忽视。

Analysis of Utilization of Antidepressants in our Hospital from 2004 -2005

Objective:To investigate the status quo and the developmental trend of application of antidepressants in our hospital.Method:A retrospective analysis of antidepressants in our hospital during 2004-2005 was made in terms of drug varieties,consumption quantity,sum,DDDs,etc.Result:The consumption sum and DDDs of antidepressants showed an up-trend by 24.76% and 23,21% respectively;SSRIs,OA and SNRIs ranked the first three places arranged by the consumption sum,while SSRIs,OA and TCA,by DDDs.The drugs having high DDDs value included flupentixol/ melitracen,fluoxetine,amitriptyline,etc.The ratio of the order of cost to that of DDDs was from 0.67 to 2.67;the daily drug cost was between 0.55 and 16.08yuan.The consumption sum of import products constituted the majority.The con- sumption of the drugs varied with the season.Conclusion:The application of new type antidepressants occupied a dominant position and showed an up-trend.TCA played an important role in the medication of depression.