^99Tc^m-MIBI心肌显像对儿童病毒性心肌炎的临床意义

目的 评价~(99)Tc~(m)-甲氧基异丁基异晴(MIBI)心肌显像对儿童病毒性心肌炎诊断和病情观察的价值。方法 对38例住院患儿(15例确诊、23例疑似病毒性心肌炎)行~(99)Tc~m-MIBI心肌断层显像,并对照7例正常儿重。全部对象均行临床常规检查。将左心室心肌划分为9个节段,进行放射性分布半定量分析(0分=分布正常,1分=2个断面以上稀疏,2分=明显稀疏,3分=缺损)。结果 38例患儿心肌显像阳性23例,阳性率为61％,评分3分、2分、1分的例数分别为1例(占4%)、13例(占57％)、9例(占39％),6例为多节段稀疏。7例正常儿重心肌显像阳性1例,假阳性率为14％。~(99)Tc~m-MIBI心肌显像与临床表现及常规检查较一致;稀疏较轻者,往往疗效较好。结论 ~(99)Tc~m-MIBI心肌显像有助于儿重病毒性心肌炎的诊断,而且提供了病情监测、预后判断的有效手段。

The clinical evaluation of ~(99)Tc~m-MIBI myocardial imaging in children with viral myocarditis

Purpose To evaluate the clinical value of 99Tcm-MIBI myocardial imaging in children with viral myocarditis.Methods 38 viral myocarditis children(15 confirmed,23 doultful and 7 children as wormal controls underwent myocardial SPECT imaging. The left ventrical wall was divided into 9 segments. The four-grade scale was used for semiquantitative evalution of radionuclide distribution (RD) in the segments (0 = normal uptake 1 = radioactirity decreased over 2 sections, 2 = radioactivity decreased,markedly ,3 = nonuptake). Results Among the 38 cases ,23 cases showed positive imaging ,the positive rate was 61 % The number of patients scored 3,2,1 were 1 (4% ) , 13 (57% ), 9 ( 39% ) respectively , 6 cases showed decreased radioactivity in multi segments. There was only one postive imaging in the 7 normal subjects( 14%). The results of myocardial imaging was con cordant with clinical performance and routine examination. Conclusion The study demonstrated that 99Tcm-MIBI myocardial inaging may be useful in the diagnosis,monitoring course disease,and judgement piognosis in children viral myocarditis.