艾灸五脏俞穴治疗慢性疲劳综合征41例临床疗效观察

目的探讨艾灸五脏俞穴治疗慢性疲劳综合征(chronic fatigue syndrome,CFS)的疗效。方法选取2012年10月~2014年10月符合纳入标准的CFS患者80例,分为两组:治疗组41例,以五脏俞穴(肝俞、心俞、脾俞、肺俞、肾俞)为主穴,通过辨证分型取相应的配穴进行艾灸治疗。对照组39例,采用西药治疗。观察两组健康调查简表(the MOS 36-item short from healthy survey,SF-36)评分、疲劳量表-14(Fatigue Scale-14,FS-14)评分、血Ig A、Ig G、Ig M、TNF-α及IL-12的含量等实验室指标。结果治疗后两组FS-14积分比较,差异有统计学意义(P0.05);治疗组治疗后SF-36部分因子评分较治疗前升高(P0.01);两组治疗前血Ig A、Ig G、Ig M、TNF-α及IL-12的含量比较,差异无统计学意义(P0.05);治疗组治疗后Ig A、Ig G、Ig M含量升高,TNF-α及IL-12含量降低,与治疗前比较,差异均有统计学意义(P0.05);对照组治疗后的TNF-α及IL-12含量与治疗前比较,差异无统计学意义(P0.05),治疗组治疗后的TNF-α及IL-12含量与对照组治疗后比较,差异有统计学意义(P0.05)。结论艾灸五脏俞穴治疗慢性疲劳综合征疗效显著。

Observation of the Clinical Efficacy on 41 Cases of Chronic Fatigue Syndrome Treated with Moxibustion at Back-Shu Points of Five Zang Organs

Objective To explore the efficacy on chronic fatigue syndrome （CFS）treated with moxibusiton at back-shu points of five zang organs.Methods Eighty cases ot CFS met the inclusive criteria were collected from October 2012 to October 2014 and were divided into two groups.In a treatment group（41 cases）,the back-shu points of five zang organs Ganshu （BL18）,Xinshu （BL15）,Pishu （BL20）,Feishu （BL13）,Shenshu（BL23） were taken as the main points.The supplementary points were selected according to syndrome differentiation in moxibustion treatment.In a control group（39 cases）,the western medication was applied.The scores of the MOS 36-item short form health survey（SF-36） and the fatigue scale-14（FS-14） and the levels of laboratory indices such as IgA,IgG,lgM,TNF-α and IL-2 were observed in the two groups.Results After the treatment,FS-14 score was different significantly between the two groups （P ＜0.05）.In the treatment group,after treatment,the scores of a part of factors in SF-36 were increased as compared with those before treatment（P ＜ 0.01）.Before treatment,the levels of IgA,IgG,lgM,TNF-α and IL-2 were not different significant between the two groups （P ＞ 0.05）.After treatment,the levels of IgA,IgG and IgM in the treatment were increased and the levels of TNF-α and IL-2 were decreased in the treatment,indicating the significant differences as compared with those before treatment（P ＜ 0.05）.In the control group,after treatment,the levels of TNF-α and IL-2 were not different significantly as compared with those before treatment（P ＞0.05）.In the treatment group,after treatment,the levels of TNF-α and IL-2 were different significantly from those in the control group （P ＜ 0.05）.Conclusion Moxibustion at the back-shu points of five zang organs achieves the significant efficacy on CFS.