乌鲁木齐地区维吾尔族与汉族儿童细菌性痢疾菌型与耐药性对比研究 |
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引用本文: | 张文利,李星萍,杨好治,施星海,田居灵.乌鲁木齐地区维吾尔族与汉族儿童细菌性痢疾菌型与耐药性对比研究[J].中华医院感染学杂志,2010,20(8). |
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作者姓名: | 张文利 李星萍 杨好治 施星海 田居灵 |
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作者单位: | 乌鲁木齐儿童医院检验科,新疆,乌鲁木齐,830002 |
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基金项目: | 乌鲁木齐市"人才工程"科研基金项目 |
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摘 要: | 目的对2003~2009年乌鲁木齐地区维吾尔族与汉族儿童细菌性痢疾病原菌的不同菌型及耐药性进行对比研究,以了解志贺菌属在不同民族儿童中的分布和耐药性差异。方法采用VITEK32鉴定分离菌株;血清凝集法进行分型;根据CLSI的标准采用K-B法检测菌株对抗菌药物的耐药性;最后采用WHONET5.4和PEMS 3.1统计软件对数据进行分析。结果维汉两个民族男女儿童检出弗氏志贺菌均80.0%,分别为维族男、女童80.6%、95.8%,汉族男、女童86.0%、86.1%,以5~11月份居多,其他菌群全年散发;痢疾志贺菌与宋内志贺菌未在维吾尔族女童中发现,男童菌群总株数(188株)多于女童(132株);维吾尔族儿童中宋内志贺菌除了对亚胺培南与左氧氟沙星100.0%敏感外,对其余抗菌药物的耐药率明显高于汉族儿童;而其他几群志贺菌对多种抗菌药物的耐药率表现为维吾尔族儿童普遍低于汉族儿童。结论4种志贺菌在两个民族儿童中分布和耐药性有明显不同,应在预防控制和临床治疗细菌性痢疾时做到有的放矢,减少儿童细菌性痢疾的发病和传播。
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关 键 词: | 儿童 细菌性痢疾 耐药性 |
Strain Types and Resistance of Bacillary Dysentery Between Children of Uygur Nationality and Han Nationality in Urumqi:A Comparative Study |
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Abstract: | OBJECTIVE To compare the strain types and antibiotic resistance of bacillary dysentery between children of the Uygur nationality and the Han nationality in Urumqi from 2003 to 2009,to know the distribution and resistance difference of Shigella in different nationality children in that area.METHODS Bacterial strains were identified by VITEK32.The strain typings were performed with serological test and the drug-susceptibility was detected with K-B methods recommended by CLSI.WHONET5.4 and PEMS 3.1 were used t... |
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Keywords: | Children Bacillary dysentery Antibiotic resistance |
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