| 67例胃肠道间质瘤临床病理及免疫组化研究 |
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| 引用本文： | 李潮,宋丁.67例胃肠道间质瘤临床病理及免疫组化研究[J].中国实验诊断学,2006,10(3):250-252. |
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| 作者姓名： | 李潮 宋丁 |
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| 作者单位： | 1. 锦州医学院附属第一医院病理科,辽宁,锦州,121000
2. 吉林大学中日联谊医院病理科,吉林,长春,130033 |
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| 摘 要： | 目的探讨胃肠道间质瘤（gastrointestinal stromal tumor，GIST）的临床病理、免疫组化特点。方法观察67例胃肠道间质瘤形态学特征及免疫组化染色。结果61．2％胃肠道间质瘤发生在小肠，瘤细胞为梭形或上皮样，或两者混合存在，胞浆嗜酸性较弱，免疫组化表型为CD34＋，CD117＋。结论胃肠道间质瘤有较独特的免疫组化表型，免疫组化可协助鉴别诊断。
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| 关 键 词： | 胃肠道间质瘤 病理 免疫组化 |
| 文章编号： | 1007-4287（2006）03-0250-03 |
| 收稿时间： | 2005-10-18 |
| 修稿时间： | 2005年10月18 |
Gastrointestinal stromal tumors: A pathomorphologic and immunohistochemical study of 67 cases |
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| LI Chao,SONG Ding.Gastrointestinal stromal tumors: A pathomorphologic and immunohistochemical study of 67 cases[J].Chinese Journal of Laboratory Diagnosis,2006,10(3):250-252. |
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| Authors: | LI Chao SONG Ding |
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| Abstract: | Objective To investigate the pathological and immunohistochemical features of gastrointestinal stromal tumors(GIST).Methods 67 cases of GIST were studied by routine stain and immunohistochemistry.Results 61.2% of the tumors originated in the small intestine.The neoplastic cells of GIST were spindle,epithelioid or both in different proportion,have a lesser degree of cytoplasmic eosinophilia.The immunophenotype of GIST was CD34+,CD117+.Conclusion GIST is with special immunophentype.The immunnohistochemistry is useful for differential diagnosis. |
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| Keywords: | gastrointestinal stromal tumors pathologic immunohistochemistry |
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