| 西地那非在高原的抗低氧效果观察 |
| |
| 引用本文： | 张西洲,崔建华,马广全,高亮,哈振德,王宏运,李彬.西地那非在高原的抗低氧效果观察[J].高原医学杂志,2009,19(3):1-3. |
| |
| 作者姓名： | 张西洲 崔建华 马广全 高亮 哈振德 王宏运 李彬 |
| |
| 作者单位： | 新疆叶城解放军第十八医院,844900 |
| |
| 摘 要： | 目的：观察西地那非在高原的抗低氧效果。方法：受试者为海拔3700m习服半年和海拔5380m习服2个月的男性士兵各10名,均采用口服同种胶囊的西地那非（西地那非组）和安慰剂（安慰剂组）进行自身对比踏阶负荷运动双盲实验。结果：海拔3700m西地那非组与安慰剂组比较,安静状态下SaO2显著增高（P〈0.05）,心率虽有降低,但无统计学意义（P〉0.05）;踏阶负荷运动后即刻心率显著降低,SaO2显著增高（P〈0.05）;台阶指数显著增高（P〈0.05）。海拔5380m西地那非组与安慰剂组比较,安静状态下和踏阶负荷运动后即刻心率均显著降低,SaO2均显著增高（P〈0.05）;台阶指数显著增高（P〈0.05）。结论：在高原口服西地那非可迅速改善低氧血症,增强运动能力。
|
| 关 键 词： | 高海拔 西地那非 血氧饱和度 心率 台阶指数 |
The Anti-Hypoxia Effect of Sildenafil at Different Geographic Altitude |
| |
| Zhang Xizhou,Cui Jianhua,Ma Guangquan,Gao Liang,Ha Zhende,Wang Hongyun,Li Bin.The Anti-Hypoxia Effect of Sildenafil at Different Geographic Altitude[J].Journal of High Altitude Medicine,2009,19(3):1-3. |
| |
| Authors: | Zhang Xizhou Cui Jianhua Ma Guangquan Gao Liang Ha Zhende Wang Hongyun Li Bin |
| |
| Institution: | Zhang Xizhou,Cui Jianhua,Ma Guangquan,Gao Liang,Ha Zhende,Wang Hongyun,Li Bin The 18th Hospital of PLA,Xinjiang Yecheng(844900) |
| |
| Abstract: | Objective:To determine the anti-hypoxia effect of sildenafil at different geographic altitude.Methods:This was a double-blind study in the test group(oral sildenafil) and the control group(oral placebo) respectively,we selected 10 male soldiers acclimated 3 700m altitudes for 6 months at first who ranged in age from 18 to 20 years,and 10 male soldiers acclimated 5 380m altitudes for 2 months at first who ranged in age 18 to 21 years.The efficacy of anti-hypoxia of sildenafil or placebo was assessed by self-... |
| |
| Keywords: | High altitude Sildenafil SaO_2 HR Step test indexes |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
