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Mucosal vaccines: high-tech reagents for low-tech immunization
Affiliation:1. Division of Medical Oncology, University of Ottawa, Ottawa, Ontario, Canada;2. Division of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, Colorado;3. Division of Renal Diseases and Hypertension, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado;4. Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado;5. Division of Allergy and Immunology, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, Colorado;6. Pathology Shared Resource, Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado;7. Department of Medicine, University of Colorado, Aurora, Colorado;8. Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia
Abstract:Antigens are usually poorly immunogenic when administered orally or intranasally and a variety of approaches have been designed to overcome this problem. Recently, the progress of six projects involving 24 laboratories funded by the ‘Human and Veterinary Vaccines’ section of the EC-Biotechnology programme were discussed at a meeting in Luxembourg.
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