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Hyperpolarized [1-13C] pyruvate MRSI to detect metabolic changes in liver in a methionine and choline-deficient diet rat model of fatty liver disease |
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| Authors: | Joao Piraquive Agudelo Yaewon Kim Shubhangi Agarwal Renuka Sriram Robert Bok John Kurhanewicz Aras N. Mattis Jacquelyn J. Maher Cornelius von Morze Michael A. Ohliger |
| Affiliation: | 1. Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California, USA;2. University of California, San Francisco, Liver Center, University of California, San Francisco, San Francisco, California, USA Department of Pathology, University of California, San Francisco, San Francisco, California, USA;3. University of California, San Francisco, Liver Center, University of California, San Francisco, San Francisco, California, USA Department of Medicine, Division of Gastroenterology, University of California, San Francisco, San Francisco, California, USA;4. Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA |
| Abstract: | |
| Keywords: | fatty liver dynamic nuclear polarization hyperpolarized carbon methionine choline deficiency NASH oxidative stress |