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The selective culture of keratinocytes using a cytotoxic antifibroblast monoclonal antibody
Authors:BA GUSTERSON  PAW EDWARDS  CS FOSTER  AM NEVILLE
Institution:Ludwig Institute for Cancer Research, London Branch, The Royal Marsden Hospital, Downs Road, Sutton, Surrey SM2 5PX
Abstract:A technique is described for the selective killing of fibroblasts in primary cultures and subcultures of human keratinocytes using a monoclonal antibody raised against human fibroblasts. The antibody kills fibroblasts by complement mediated cytotoxicity but is not toxic to keratinocytes.
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