The selective culture of keratinocytes using a cytotoxic antifibroblast monoclonal antibody |
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Authors: | BA GUSTERSON PAW EDWARDS CS FOSTER AM NEVILLE |
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Institution: | Ludwig Institute for Cancer Research, London Branch, The Royal Marsden Hospital, Downs Road, Sutton, Surrey SM2 5PX |
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Abstract: | A technique is described for the selective killing of fibroblasts in primary cultures and subcultures of human keratinocytes using a monoclonal antibody raised against human fibroblasts. The antibody kills fibroblasts by complement mediated cytotoxicity but is not toxic to keratinocytes. |
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