直肠腔内超声与相控阵线圈磁共振在直肠癌术前局部分期中的Meta分析

目的 运用Meta分析比较直肠腔内超声（ERUS）与相控阵线圈磁共振（MRI）对直肠癌术前局部分期的准确率。方法 检索PubMed、Cochrane Library、OVID、Web of Science和CNKI电子数据库确定ERUS和相控阵线圈MRI对直肠癌术前局部分期准确率的相关临床随机对照研究，建库时间更新至2019年1月。使用STATA 12.0和RevMan 5.3软件进行Meta分析，使用Bgger's检验方法检测发表偏倚。结果 共纳入7项研究，发表年限为2005年~2014年，中国3篇，意大利2篇，土耳其1篇，西班牙1篇，共纳入416例患者。Meta分析结果显示，ERUS与相控阵线圈MRI对直肠癌术前T分期的准确率比较，差异无统计学意义（OR=0.91，95%CI:0.63~1.32，P=0.619）。对于直肠癌术前N分期，相控阵线圈MRI的准确率高于ERUS，差异有统计学意义（OR=0.58，95%CI:0.41~0.82，P=0.002）。Bgger's检验结果提示纳入研究无发表偏倚（Pr＞|z|=0.453；P＞0.05）。结论 通过Meta分析发现在直肠癌术前T分期，ERUS与相控阵线圈MRI的准确率相近，而在直肠癌术前N分期，相控阵线圈MRI相对于ERUS具有更高的准确率。

Meta-analysis of Intra-rectal Ultrasound and Phased-array Magnetic Resonance in the Preoperative Partial Phase of Rectal Cancer

Objective To compare the accuracy of intra-rectal ultrasound (ERUS) and phased-array magnetic resonance (MRI) in the preoperative partial phase of rectal cancer with meta-analysis.Methods The PubMed, Cochrane Library, OVID, Web of Science, and CNKI electronic databases were used to determine the clinical randomized controlled trials of ERUS and phased-array coil MRI for preoperative partial accuracy of rectal cancer. The database was updated to January 2019. Meta-analysis was performed using STATA 12.0 and RevMan 5.3 software, and publication bias was detected using Bgger's test method. Results A total of 7 studies were included, with a publication period of 2005 to 2014, 3 in China, 2 in Italy, 1 in Turkey, and 1 in Spain. A total of 416 patients were included. Meta-analysis showed that the accuracy of ERUS and phased-array coil MRI for preoperative T staging of rectal cancer was not statistically significant (OR=0.91,95%CI:0.63~1.32,P=0.619).For preoperative N staging of rectal cancer, the accuracy of phased array coil MRI was higher than that of ERUS, and the difference was statistically significant (OR=0.58,95%CI:0.41~0.82,P=0.002).Bgger's test results suggest that there is no publication bias in the included study (Pr>|z|=0.453;P>0.05).Conclusion Meta-analysis found that the preoperative T stage of rectal cancer, ERUS and phased array coil MRI accuracy is similar, and in the preoperative N stage of rectal cancer, phased array coil MRI has higher accuracy than ERUS.