OCT测量分析视网膜中央静脉阻塞黄斑囊样水肿时 黄斑区视网膜厚度变化研究

目的 研究频域光学相干断层扫描仪Cirrus HD-OCT对视网膜中央静脉阻塞黄斑囊样水肿（CRVO-CME）时黄斑区视网膜厚度的变化情况。方法 纳入我院2017年11月~2019年2月收治的45例（60眼）CRVO-CME患者作为研究组，另选取45例（60眼）来我院进行体检的健康志愿者作为对照组。所有患者均行HD-OCT检查，根据早期糖尿病视网膜病变治疗研究（ETDRS）视力表对黄斑区进行分区，观察两组眼黄斑区视网膜厚度情况，分析黄斑区视网膜厚度与最佳矫正视力（BCVA）的关系。结果 研究组F、IT、II、IN、IS、OT、OI、ON以及OS黄斑区9个分区的视网膜厚度均大于对照组，差异有统计学意义（P＜0.05）。IT、II、IN、IS黄斑区4个内分区厚度组间比较，差异无统计学意义（P＞0.05）；OT、OI、ON以及OS黄斑区4个外分区厚度组组间比较，差异无统计学意义（P＞0.05）。CRVO-CME患者FT以及Fmax与BCVA存在负相关性（P＜0.05）。结论 CRVO-CME患者视网膜各分区均比正常人视网膜更厚，对CRVO-CME患者进行HD-OCT测量对视网膜厚度的判断较准确，为临床诊治CRVO-CME提供了有力依据。

OCT Measurement of Macular Retinal Thickness Changes during Macular Cystic Edema of Central Retinal Vein Occlusion

Abstract:Objective To investigate the changes of retinal thickness in the macular area of the central retinal vein occlusion macular cyst-like edema (CRVO-CME) by frequency domain optical coherence tomography Cirrus HD-OCT. Methods A total of 45 patients (60 eyes) with CRVO-CME admitted to our hospital from November 2017 to February 2019 were enrolled in the study. 45 healthy subjects (60 eyes) were enrolled in our hospital as healthy controls. . All patients underwent HD-OCT examination. The macular area was segmented according to the Early Diabetic Retinopathy Treatment Study (ETDRS) visual acuity chart. The retinal thickness of the macular area was observed in both groups. The retinal thickness and best corrected visual acuity (BCVA) were analyzed. Relationship. Results The retinal thickness of the study group F, IT, II, IN, IS, OT, OI, ON and OS macular area both greater than the control group,the difference was statistically significant (P<0.05). There were no significant differences in the thickness of the four internal compartments between the IT, II, IN, and IS macular areas (P>0.05). There were no significant differences between the OT, OI, ON and OS yellow plaque thickness groups (P>0.05). There was a negative correlation between FT and Fmax and BCVA in CRVO-CME patients (P<0.05). Conclusion The retinal sections of CRVO-CME patients are thicker than normal human retina. The HD-OCT measurement of CRVO-CME patients is more accurate in the determination of retinal thickness, which provides a powerful basis for clinical diagnosis and treatment of CRVO-CME.