| CA153在乳腺癌免疫治疗中的作用 |
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| 引用本文： | 曹涤非,黄国庆,薛佳莹,吴琼,王雷,李瑶. CA153在乳腺癌免疫治疗中的作用[J]. 实用肿瘤学杂志, 2019, 33(6): 566-569. DOI: 10.11904/j.issn.1002-3070.2019.06.018 |
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| 作者姓名： | 曹涤非 黄国庆 薛佳莹 吴琼 王雷 李瑶 |
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| 作者单位： | 黑龙江省科学院高技术研究院(哈尔滨 150020) |
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| 摘 要： | 乳腺癌是女性常见的恶性肿瘤,免疫治疗是临床上取得较好效果的治疗手段之一。CA153可在乳腺癌免疫应答中作为特异性抗原激活免疫应答;参与T细胞活化;靶向结合多肽疫苗,增强免疫应答;诱导树突状细胞成熟,清除体内癌细胞等。因此CA153在乳腺癌的免疫应答和治疗中具有重要的作用,可作为乳腺癌免疫治疗的新靶点。
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| 关 键 词： | CA153 乳腺癌 免疫治疗 靶点 |
| 收稿时间： | 2019-06-13 |
The role of CA153 in breast cancer immunotherapy |
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| CAO Difei,HUANG Guoqing,XUE Jiaying,WU Qiong,WANG Lei,LI Yao. The role of CA153 in breast cancer immunotherapy[J]. Journal of Practical Oncology, 2019, 33(6): 566-569. DOI: 10.11904/j.issn.1002-3070.2019.06.018 |
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| Authors: | CAO Difei HUANG Guoqing XUE Jiaying WU Qiong WANG Lei LI Yao |
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| Affiliation: | Institute of Advanced Technology,Heilongjiang Academy of Sciences,Harbin 150020,China |
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| Abstract: | Breast cancer is a common malignant tumor in women,and immunotherapy is one of the treatments with a good clinical prognosis.CA153 can activate immune response as a specific antigen in breast cancer immune response;participate in T cell activation;target binding peptide vaccine;enhance immune response;induce dendritic cell maturation,and eliminate cancer cells in vivo.Therefore,CA153 plays an important role in the immune response and treatment of breast cancer,and can be used as a new target for breast cancer immunotherapy. |
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| Keywords: | CA153 Breast cancer Immunotherapy Target |
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