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外泌体在结直肠癌中的研究进展
引用本文:李在明,魏正强.外泌体在结直肠癌中的研究进展[J].医学信息,2019,0(3):42-44.
作者姓名:李在明  魏正强
作者单位:(重庆医科大学附属第一医院胃肠外科,重庆 400000)
摘    要:近年来,由于对外泌体的不断认识和了解,研究外泌体已成为当下的热点,外泌体是细胞分泌的一种纳米级囊泡结构,可来源于机体正常细胞及肿瘤细胞,在血液、唾液、尿液、母乳等多种体液中均有分布,其参与许多生物学和病理学过程,主要是由于它们在细胞间通讯作用,源自结直肠癌(CRC)细胞的外泌体与肿瘤发生、进展、转移、预后等相关。本文就外泌体在结直肠癌中的研究进展进行综述。

关 键 词:结直肠癌  外泌体  标志物  肿瘤微环境

Research Progress of Exosomes in Colorectal Cancer
LI Zai-ming,WEI Zheng-qiang.Research Progress of Exosomes in Colorectal Cancer[J].Medical Information,2019,0(3):42-44.
Authors:LI Zai-ming  WEI Zheng-qiang
Institution:(Department of Gastroenterology,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400000,China)
Abstract:In recent years, due to the continuous understanding and understanding of exosomes, research on exosomes has become a hot spot. Exosomes are a kind of nano-sized vesicle structure secreted by cells, which can be derived from normal cells and tumor cells in the blood. It is distributed in various body fluids such as saliva, urine, and breast milk. It is involved in many biological and pathological processes, mainly due to their intercellular communication, and the exosomes derived from colorectal cancer (CRC) cells. Tumor development, progression, metastasis, prognosis, etc. This article reviews the research progress of exosomes in colorectal cancer.
Keywords:Colorectal cancer  Exosomes  Markers  Tumor microenvironment
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