高血压患者发生射血分数保留心衰的危险因素分析

目的 分析高血压患者发生射血分数保留心力衰竭的危险因素,为该类患者的预防提供参考依据。方法 回顾性分析2016年1月~2018年12月我院102例原发性高血压患者的临床资料，将高血压合并射血分数保留的心力衰竭患者50例作为观察组，以原发性高血压非心衰患者52例作为对照组，比较两组临床资料，包括性别、年龄、BMI、吸烟史、饮酒史、房颤、冠心病、糖尿病、高尿酸血症、肾功能不全、脑卒中、低血钾、血脂异常、贫血、呼吸睡眠暂停病史，分析其与高血压合并射血分数保留心衰的相关性，多因素回归分析高血压患者发生射血分数保留心衰的危险因素。结果 两组性别、BMI、年龄、吸烟史、房颤、冠心病、糖尿病、高尿酸血症、肾功能不全、贫血的发病率比较，差异有统计学意义（P＜0.05）；两组饮酒史、低血钾、脑卒中、血脂异常、呼吸睡眠暂停发病率比较，差异无统计学意义（P＞0.05）。Pearson相关性分析结果显示，性别、BMI、年龄，吸烟史、房颤、冠心病、糖尿病、高尿酸血症、肾功能不全、贫血与高血压合发生射血分数保留心衰呈正相关（P＜0.05）。Logistic多因素回归分析结果显示，女性、超重、吸烟、房颤、高尿酸血症为高血压患者发生射血分数保留心衰的独立危险因素。结论 女性、超重、吸烟、房颤、高尿酸血症为高血压合并射血分数保留心衰的危险因素。临床工作应重视对女性高血压患者基础疾病控制，同时重视对患者不良生活习惯的干预治疗，改善机体异常症状，以降低射血分数保留心衰的发生进展。

Analysis of Risk Factors for the Occurrence of Heart Failure in Patients with Hypertension

Objective Analysis of the risk factors of heart failure in patients with hypertension to preserve heart failure, provide a reference for the prevention of such patients.Methods A retrospective analysis of 102 patients with essential hypertension admitted to our hospital from January 2016 to December 2018, 50 patients with heart failure and hypertension with ejection fraction retained as observation group, with essential hypertension 52 patients with non-heart failure were used as the control group. The clinical data， including sex, age, BMI, smoking history, drinking history， atrial fibrillation, coronary heart disease, diabetes, hyperuricemia were compared between the two groups, renal insufficiency, stroke, hypokalemia, dyslipidemia, anemia, respiratory sleep apnea history, analysis of its association with hypertension with ejection fraction to preserve heart failure, multivariate regression analysis of high blood pressure patients with ejection fraction Preserve the risk factors for heart failure.Results There were significant differences in gender, BMI, age, and smoking history and the incidence of atrial fibrillation, coronary heart disease, diabetes, hyperuricemia, renal insufficiency, and anemia was statistically significant (P<0.05). There was no significant difference in the incidence of drinking history， hypokalemia, stroke, dyslipidemia, and respiratory sleep pauses between two groups (P>0.05). Pearson correlation analysis showed that gender, BMI, age, smoking history, atrial fibrillation, coronary heart disease, diabetes, hyperuricemia, renal insufficiency, anemia and hypertension were positively correlated with the ejection fraction to preserve heart failure (P<0.05). Logistic multivariate regression analysis showed that women, overweight, smoking, atrial fibrillation, and hyperuricemia were independent risk factors for the occurrence of heart failure in patients with hypertension.Conclusion Female, overweight, smoking, atrial fibrillation, and hyperuricemia are risk factors for hypertension and combined ejection fraction to preserve heart failure. Clinical work should pay attention to the basic disease control of female hypertensive patients, and pay attention to the intervention treatment of patients with bad living habits, improve the abnormal symptoms of the body, in order to reduce the ejection fraction and preserve the progress of heart failure.