Xpert MTB/RIF技术对结核分枝杆菌的诊断价值

目的 对Xpert MTB/RIF技术检测结核分枝杆菌（MTB）的结果进行分析并评估其价值。方法 采集2017年10月~2018年10月本院就诊疑为结核分枝杆菌感染的患者共580例，利用Xpert MTB/RIF技术对其痰液（或体液）标本进行DNA检测，同时将标本进行固体培养及涂片抗酸染色并对检测结果进行比较。结果 Xpert MTB/RIF技术检测MTB的阳性率为18.97%（110/580），和固体培养法的阳性率18.62%（108/580）相比差异无统计学意义（P＞0.05）；和抗酸染色法的阳性率15.00%（87/580）相比则更为敏感，差异有统计学意义（P＜0.05）。 结论 Xpert MTB/RIF检测技术和固体培养法不相上下，且由于抗酸染色法，可以用于MTB的快速筛选。

Diagnostic Value of Xpert MTB/RIF Technique for Mycobacterium Tuberculosis

Objective To analyze and evaluate the results of Xpert MTB/RIF detection of Mycobacterium tuberculosis (MTB).Methods A total of 580 patients with suspected Mycobacterium tuberculosis infection were enrolled in our hospital from October 2017 to October 2018. The sputum (or body fluid) specimens were tested for DNA by Xpert MTB/RIF technique. Solid culture and smear acid-fast staining and comparison of test results.Results The positive rate of MTB detected by Xpert MTB/RIF technique was 18.97%(110/580), and the positive rate of solid culture method was 18.62% (108/580),the difference was not statistically significant (P>0.05); The positive rate of staining was 15.00%(87/580), which was more sensitive,the difference was statistically significant(P<0.05). Conclusion Xpert MTB/RIF detection technology is comparable to solid culture method, and can be used for rapid screening of MTB due to acid-fast staining.