蜂毒清1号对轻中度毒蜂蜇伤患者心肝肾功能影响的临床研究

目的 探讨自拟中药（蜂毒清颗粒1号）对轻中度毒蜂蛰伤患者的临床疗效。方法 选择2016年5月~2018年5月我院急诊科收治的轻中度蜂蛰伤患者420例，随机分为治疗组与对照组，各210例。对照组患者给予常规治疗方案，治疗组在对照组基础上经中医辨证给予蜂毒清1号颗粒口服。比较两组临床疗效、肝肾功能恢复情况，心肌酶水平及住院时间。结果 治疗组总有效率为98.09%，高于对照组的93.81%，差异有统计学意义（P＜0.05）；治疗组的心肌酶、肝功能指标均较对照组下降，差异有统计学意义（P＜0.05）；两组患者肾功能指标比较，差异无统计学意义（P＞0.05）；治疗组患者住院时间少于对照组（4.15±1.50）d vs （6.25±2.05）d]，差异有统计学意义（P＜0.05）。结论 常规西医治疗联合蜂毒清颗粒1号能够改善轻中度蜂蜇伤患者病情，提高临床疗效，缩短病程时间。另外，对于轻中度蜂蛰伤患者，早期应重视其心肌酶、肝功能变化情况。

Clinical Study on the Effect of Fengduqing No.1 on Heart,Liver and Kidney Function of Patients with Mild to Moderate Poison Bee Sting

Objective To investigate the clinical efficacy of self-made traditional Chinese medicine (Fengduqing Granule No. 1) in patients with mild to moderate bee sting.Methods A total of 420 patients with mild to moderate bee stings admitted to the emergency department of our hospital from May 2016 to May 2018 were randomly divided into treatment group and control group, 210 cases each. The patients in the control group were given a conventional treatment plan, and the treatment group was given Fengduqing Granule No. 1 orally by TCM syndrome differentiation on the basis of the control group. The clinical efficacy, liver and kidney function recovery, myocardial enzyme level and hospitalization time were compared between the two groups.Results The total effective rate of the treatment group was 98.09%, which was higher than that of the control group 93.81%,the difference was statistically significant (P<0.05).The myocardial enzymes and liver function indexes of the treatment group were lower than the control group,the difference was statistically significant (P<0.05);There was no significant difference in renal function between the two groups (P>0.05).The hospitalization time of the treatment group was less than that of the control group (4.15±1.50)d vs (6.25±2.05)d],the difference was statistically significant (P<0.05).Conclusion Conventional Western medicine combined with Fengduqing Granule No. 1 can improve the condition of patients with mild to moderate bee sting, improve clinical efficacy and shorten the course of disease. In addition, for patients with mild to moderate bee sting, early attention should be paid to changes in myocardial enzymes and liver function.