盐酸氨溴索注射液联合酚妥拉明注射液治疗小儿重症肺炎的疗效

目的 观察盐酸氨溴索注射液联合酚妥拉明注射液治疗小儿重症肺炎的临床疗效。方法 选取2017年2月~2018年2月在我院诊治的140例小儿重症肺炎患儿作为研究对象，随机分为对照组和观察组，各70例。对照组采用常规治疗，观察组在对照组基础上给予盐酸氨溴索注射液联合酚妥拉明注射液治疗，对比两组临床治疗有效率、临床症状消失时间（发热、咳嗽、气促、湿啰音、心衰）及不良反应发生情况。结果 观察组治疗总有效率为94.28%，高于对照组的78.57%，差异有统计学意义（P＜0.05）；观察组临床症状消失时间（发热、咳嗽、气促、湿啰音、心衰）均短于对照组，差异有统计学意义（P＜0.05）；观察组不良反应发生率为5.71%，低于对照组的28.57%，差异有统计学意义（P＜0.05）。结论 盐酸氨溴索注射液联合酚妥拉明注射液治疗小儿重症肺炎疗效确切，临床症状消退时间短，应用安全性高，可促进患儿的快速恢复。

Efficacy of Ambroxol Hydrochloride Injection Combined with Phentolamine Injection inthe Treatment of Severe Pneumonia in Children

Abstract:Objective To observe the clinical efficacy of ambroxol hydrochloride injection combined with phentolamine injection in the treatment of severe pneumonia in children.Methods A total of 140 children with severe pneumonia in our hospital from February 2017 to February 2018 were enrolled in the study. They were randomly divided into the control group and the observation group, 70 cases each. The control group was treated with conventional therapy. The observation group was treated with ambroxol hydrochloride injection combined with phentolamine injection on the basis of the control group. The clinical treatment efficiency and clinical symptom disappearance time (fever, cough, shortness of breath, wetness Voice, heart failure) were compared between the two groups and adverse reactions.Results The total effective rate of the observation group was 94.28%, which was higher than that of the control group 78.57%,the difference was statistically significant (P<0.05). The clinical symptoms disappeared in the observation group (fever, cough, shortness of breath, wet voice, heart failure),the difference was statistically significant (P<0.05). The incidence of adverse reactions in the observation group was 5.71%, which was lower than that in the control group 28.57%,the difference was statistically significant (P<0.05). Conclusion Ambroxol hydrochloride injection combined with phentolamine injection is effective in the treatment of severe pneumonia in children. The clinical symptoms are short and the application safety is high, which can promote the rapid recovery of children.