婚姻状况对少突胶质细胞瘤患者预后的影响

目的:探讨少突胶质细胞瘤患者婚姻状况与预后之间的关系。方法:纳入SEER数据库中自1973-2015年诊断为少突胶质细胞瘤的4 282例患者。通过Kaplan-Meier法分析患者生存率，Cox回归模型分析影响生存的独立危险因素。结果:单因素分析显示，性别、年龄、手术情况、原发灶部位、婚姻状况与少突胶质细胞瘤患者生存期相关（P<0.01）。多因素分析发现，婚姻状况是患者生存的独立预后因素（P<0.05），在相同性别、年龄范围、手术治疗情况下，丧偶仍是患者的独立危险因素（P<0.01）。结论:婚姻状况与少突胶质细胞瘤患者生存期密切相关，丧偶增加患者的死亡风险。

Effects of marital status on patient prognosis in oligodendroglioma

Objective: To investigate the impact of marital status on patient prognosis in oligodendroglioma. Methods:We collected 4282 eligible patients with oligodendroglioma from SEER database from 1973 to 2015. Kaplan-Meier methods were used to analyze the patients’ survival, and Cox regression models were applied to analyze independent risk factors for patients’overall survival in oligodendroglioma. Results: Univariate analysis showedthat gender, age,surgery status, and primary siteandmarital status were significantly associated with patients’ overall survival in oligodendroglioma（P <0.01）. Multivariate analysis found that marital status wasthe independent prognostic factor for patients’ overall survival（P <0.05）. Widowed remained the independent risk factor for patients with the same gender, age range or surgery status（P<0.01）. Conclusion: Marital status might be closely associated with patients’ overall survival in oligodendroglioma, and widowed may increase the risk of death in patients.