初诊青年2型糖尿病临床特点及危险因素分析

目的 明确青年初诊2型糖尿病的临床特点并探讨相关危险因素，为预防高危因素青年人发生2型糖尿病提供理论依据。方法 选择我院内分泌科2017年1月~2018年3月住院的313例初诊2型糖尿病患者，以40岁为界将其分为青年组及非青年组，分析患者的临床特点及危险因素。结果 青年组男性构成率为75.76%，非青年组男性构成率为55.87%，两组性别构成率比较，差异有统计学意义（P＜0.05）；青年组收缩压（128.88±17.97）mmHg低于非青年组（137.47±19.44）mmHg，差异有统计学意义（P＜0.05）；青年组体重指数（26.02±4.80）kg/m2高于非青年组（24.52±3.41）kg/m2，差异具有统计学意义（P＜0.05）；青年组甘油三酯（3.62±3.44）mmol/L高于非青年组（2.87±3.35）mmol/L，差异有统计学意义（P＜0.05）；青年组高密度脂蛋白（1.03±0.35）mmol/L低于非青年组（1.14±0.37）mmol/L，差异有统计学意义（P＜0.05）。初诊2型糖尿病为青年人的危险因素为性别（OR=2.07，95%CI:1.09~3.93，P＜0.05）、BMI（OR=2.10，95%CI:1.14~3.18，P＜0.05）及HDL-C（OR=1.98，95%CI:1.11~3.52，P＜0.05）。结论 男性、超重及肥胖、低高密度脂蛋白是青年人发生2型糖尿病的危险因素。

Analysis of Clinical Features and Risk Factors of Type 2 Diabetes in Newly Diagnosed Youth

Abstract:Objective To determine the clinical characteristics of newly diagnosed type 2 diabetes in young people and to explore related risk factors, so as to provide a theoretical basis for prevention of type 2 diabetes in young people with high risk factors.Methods 313 patients with newly diagnosed type 2 diabetes who were hospitalized from January 2017 to March 2018 in our hospital were divided into young and non-youth groups by age 40, and the clinical characteristics and risk factors were analyzed.Results The male composition rate was 75.76% in the youth group and 55.87% in the non-youth group. The gender composition rate was statistically significant (P<0.05). The young group systolic blood pressure (128.88±17.97) mmHg lower than the non-youth group (137.47±19.44) mmHg, the difference was statistically significant (P<0.05); the body mass index (26.02±4.80) kg/m2 in the young group was higher than that in the non-youth group (24.52±3.41) kg/m2, the difference was statistically significant (P<0.05); Triglyceride (3.62±3.44) mmol/L was higher than non-youth group (2.87±3.35) mmol/L, the difference was statistically significant (P<0.05); high density lipoprotein (1.03±0.35) mmol/L lower than the non-youth group (1.14±0.37) mmol/L, the difference was statistically significant (P<0.05). The risk factors for newly diagnosed type 2 diabetes were younger (OR=2.07, 95%CI: 1.09~3.93,P<0.05), BMI (OR=2.10, 95%CI: 1.14~3.18,P<0.05) and HDL-C (OR=1.98,95%CI:1.11 to 3.52,P<0.05).Conclusion Male, overweight and obese, low-density lipoprotein is risk factor for developing type 2 diabetes in young adults.