| 卡托普利对慢性肺心病患者急性血液动力学及激素变化的研究 |
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| 引用本文： | 汤宝鹏,程祖亨,黄亦芬,张爱伦,左希奎,陈茹兰,方志高,张立生.卡托普利对慢性肺心病患者急性血液动力学及激素变化的研究[J].中华结核和呼吸杂志,1995(5). |
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| 作者姓名： | 汤宝鹏 程祖亨 黄亦芬 张爱伦 左希奎 陈茹兰 方志高 张立生 |
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| 作者单位： | 新疆医学院第一附属医院心内科，新疆医学院第一附属医院呼吸科，新疆医学院第一附属医院核医学科 |
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| 摘 要： | 以２０例肺心病心力衰竭并呼吸衰竭患者及１１例健康者为对象，进行静脉注射卡托普利治疗肺心病的急性血液动力学及激素变化的临床研究。结果表明，静脉注射卡托普利能快速降低心脏前后负荷，降低肺动脉压力，增加心排血量，同时抑制肾素系统活性，降低血浆甲状腺素及心钠素水平，使急、重症肺心病患者临床症状迅速缓解，但对即刻血气变化无明显影响。
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| 关 键 词： | 肺心病，血液动力学，激素类，卡托普利 |
A researcb of acute hemodynamics and hormonalchanges of intravenous captopril in patients with corpulmonale and pulmonary hypertension. |
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| TangBaopeng,Cheng Zuheng,Huang Yifen.et al..A researcb of acute hemodynamics and hormonalchanges of intravenous captopril in patients with corpulmonale and pulmonary hypertension.[J].Chinese Journal of Tuberculosis and Respiratory Diseases,1995(5). |
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| Authors: | TangBaopeng Cheng Zuheng Huang Yifen |
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| Abstract: | n 20 patients of cor pulmonale with heart failureand respiratory failure and in 11 healthy men . after in-travonous captopril injection, acute hemodynamic andhormonal change were observed. The results indicatedthat intravenous captopril injection rapidly reducetl car-diac preload and afterload, reduced pulmonary arterialpressure,increased cardiac output. inhibited renin sys-tem activity,decreased plasma level of thyroxin and a-trial patriuretic peptide.A rapid symptomatic improve-ment in patients with acute or severe cor pulmonale wasshown and there was no significant effect on blood gasimmediattely. |
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| Keywords: | Pulmonary heart disease Hemody-namies Hormones Captopril |
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