EARLY DIAGNOSIS IN POST RENAL TRANSPLANT OPPORTUNISTIC INFECTIONS: A FRESH LOOK |
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| Authors: | GS CHOPRA AS NARULA PS REDDY JR BHARDWAJ |
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| Affiliation: | *Classified Specialist Pathology & Transplant Immunologist, Command Hospital (EC), Calcutta 27;+Classified Specialist Medicine & Nephrology, INHS, Asvini, Mumbai 5;#Senior Advisor Pathology, Army Hospital (R & R), Delhi Cantt;**Commandant AFMSD Delhi Cantt |
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| Abstract: | A total of 86 renal transplant patients who were transplanted with live related donor (LRD) and live unrelated donor (LURD) kidneys were studied for opportunistic infections. Immune diagnosis of Toxoplasma, Cytomegalovirus (CMV), Herpes-simplex virus type II (HSV-2), Aspergillosis and Tuberculosis was carried out in these patients along with sputum examination, CSF studies and biopsy of lymphnode and other tissues in few cases. A high degree of Toxoplasma, CMV & HSV-2 positivity was seen in transplanted patients. However sensitivity of serological diagnosis of tuberculos was found to be low with standard criteria, which increased significantly when modified criteria were used. It is concluded that regular immunological monitoring should be carried out in transplanted patients so as to reach an early diagnosis and management of opportunistic infections.KEY WORDS: Immune diagnosis, Opportunistic infections, Transplantation |
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| Keywords: | Immune diagnosis Opportunistic infections Transplantation |
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