亚临床肝性脑病诊断标准探讨

1978年Ｒｉｋｋｅｒｓ等对一些无肝性脑病临床症状的肝硬变患者进行了严格的心理学测试发现异常。以后渐有类似报道,并提出亚临床肝性脑病(Ｓｕｂｃｌｉｎｉｃａｌｈｅｐａｔｉｃｅｎｃｅｐｈａｌｏｒａｔｈｙ,ＳＨＥ)的概念。对ＳＨＥ诊断标准问题尚缺乏较为统一的认识。我们自1996年6月～1998年5月对60例无肝性脑病的失代偿期肝硬变患者进行了心理智力测试及诱发电位测定,认为这些检测结果对ＳＨＥ诊断确有价值。同时发现血浆内毒素水平与心理智力测试,诱发电位测定密切相关。提出ＳＨＥ应有一个综合判定的临床标准,并对标准的设置作了初…

Analysis on the diagnostic standard of sub-clinical hepatic encephalopathy.

To investigate and suggest the diagnostic standard of sub-clinical hepatic encephalopathy(SHE).Methods 60 decompensation cirrhosis patients were selected to undertake the psychometric,evoked potential,plasma endotoxin,and ammonemia tests.Results It was showed that psychometric and evoked potential abnormality rates were similar to that of other studies,and there was a close correlation between plasma endotoxin level,psychometric and evoked potential abnormalities. Conclusion The tests of psychometric,evoked potential,and plasma endotoxin can be regarded as the diagnostic standard for SHE.