New cytotoxic xenia diterpenoids from the Formosan soft coral Xenia umbellata |
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| Authors: | Duh Chang-Yih El-Gamal Ali Ali H Chiang Chin-Ying Chu Chih-Ju Wang Shang-Kwei Dai Chang-Feng |
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| Affiliation: | Department of Marine Resources, National Sun Yat-sen University, Kaohsiung, Taiwan. yihduh@mail.nsysu.edu.tw |
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| Abstract: | Seven new cytotoxic xenicane-type diterpenoids, 9-deoxyxeniloide-E (1), 9-deoxy-7,8-epoxyxeniloide-E (2), xeniolide-G (3), 9-deoxyxenialactol-C (4), xenibecin (5), xeniolide-H (6), and xenitacin (7), were isolated from the methylene chloride solubles of the Formosan soft coral Xenia umbellata. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro. |
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