Diffuse leptomeningeal involvement by a ganglioglioma in a child. Case report. |
| |
| Authors: | M R Wacker P H Cogen J E Etzell L Daneshvar R L Davis M D Prados |
| |
| Affiliation: | Department of Neurological Surgery, School of Medicine, University of California, San Francisco. |
| |
| Abstract: | Gangliogliomas are tumors composed of neuronal and glial elements that typically grow slowly by expansion only. This report describes a 20-month-old girl with a ganglioglioma that extensively involved the subarachnoid space; microscopic foci of tumor were found in the brain and spinal cord. Despite chemotherapy and radiation therapy, the child died 5 months after diagnosis. Molecular genetic analysis showed loss of chromosome 17p DNA sequences in the tumor tissue. |
| |
| Keywords: | |
|
|
