| Lambert型豪猪状鱼鳞病的光镜及电镜分析 |
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| 引用本文： | 王文慧,李邻峰,张倩,杨绍敏,姜薇,王玉英,雷鹏程,陈学荣. Lambert型豪猪状鱼鳞病的光镜及电镜分析[J]. 中国麻风皮肤病杂志, 2007, 23(1): 19-22 |
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| 作者姓名： | 王文慧 李邻峰 张倩 杨绍敏 姜薇 王玉英 雷鹏程 陈学荣 |
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| 作者单位： | 1. 北京大学第三医院皮肤科,北京,100083
2. 北京大学病理学系,北京,100083 |
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| 摘 要： | 目的：观察Lambert型豪猪状鱼鳞病的组织病理和电镜表现。方法：观察一Lambert型豪猪状鱼鳞病家系，并对皮损组织做光镜和电镜观察。结果：光镜下可见颗粒层和棘细胞上层多数双核细胞及核周厚薄不均连续的包壳结构；电镜下可见包壳结构由张力微丝组成。结论：Lambert型豪猪状鱼鳞病的显微结构，即棘细胞上层的双核细胞和核周张力微丝壳，与Curth-Macklin型豪猪状鱼鳞病相似。
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| 关 键 词： | 豪猪状鱼鳞病 壳 双核细胞 张力微丝 |
| 收稿时间： | 2006-09-11 |
| 修稿时间： | 2006-09-11 |
Pathological observation of ichthyosis hystrix Lambert type with light and electron microscopes |
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| Wang Wenhui , Li Linfeng , Zhang Qian, et al. Pathological observation of ichthyosis hystrix Lambert type with light and electron microscopes[J]. China Journal of Leprosy and Skin Diseases, 2007, 23(1): 19-22 |
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| Authors: | Wang Wenhui Li Linfeng Zhang Qian et al |
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| Affiliation: | Department of Dermatology ,Peling University Third Hospital,Beijing,100083 |
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| Abstract: | Objective: To observe pathological features of ichthyosis hystrix(IH) Lambert type with light and electron microscopes.Methods: A family of IH Lambert type was observed and pathological features of the skin lesion examined under light and electron microscopes.Results: Under light microscope,binuclear cells in granular layer and upper layer of prickle cells,and perinuclear shell formation consisted of thin or thick continuous structure was found.The shells were composed of tonofilaments under electron microspcope.(Conclusion): Binuclear cells and(tonofilament's) shells surrounding the nucleus in upper keratinocytes are characteristic features,which are similar to those reported in IH Curth-Macklin type. |
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| Keywords: | ichthyosis hystrix shell binuclear cell tonofilament |
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