清开灵注射液致儿童过敏性休克

1例4岁女童因上呼吸道感染给予清开灵注射液、利巴韦林、能量合剂治疗。清开灵注射液8 ml入5%葡萄糖注射液150 ml静脉滴注,滴注开始后约10 min,患儿手掌及颈部出现皮肤瘙痒及风团,且迅速遍及全身,面色苍白,呼吸急促,血压60/30 mm Hg(1 mm Hg=0.133 kPa)。立即停止输液,持续给氧,给予肾上腺素及地塞米松等对症处理,患儿病情逐渐好转,1 h后生命体征稳定。

Anaphylactic shock secondary to Qingkailing injection in a child

A 4-year-old girl with upper respiratory tract infection received Qingkailing injection,ribavirin,and energy mixture.The patient was given an IV infusion of Qingkailing injection 8 ml in 5% glucose 150 ml.About ten minutes after the infusion started,she developed skin pruritus and wheal on her palm and neck that rapidly progressed to involve her whole body,followed by pallor,short of breath,and a blood pressure of 60/30 mm Hg.The infusion was discontinued immediately.Oxygen inhalation and symptomatic treatment with epinephrine and dexamethasone were given.Her condition improved gradually and,one hour later,her vital signs were stable.