Spinal cord lesions in progressive supranuclear palsy: some new observations |
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Authors: | T. Kato A. Hirano M. N. Weinberg A. K. Jacobs |
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Affiliation: | (1) Bluestone Laboratory of the Division of Neuropathology, Department of Pathology, Montefiore Medical Center, 111 East 210th Street, 10467 Bronx, NY, USA;(2) Department of Laboratory Medicine and Neurology, Good Samaritan Hospital and Health Center, 45406 Dayton, OH, USA |
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Abstract: | Summary The spinal cord was examined in two cases of progressive supranuclear palsy. In both cases, cells with neurofibrillary tangles were seen in the anterior horn, posterior horn, lateral horn, Clark's column, and intermediate gray. The tangles were most frequently observed in the posterior horn. The results suggest that the spinal cord is involved in the pathological process of progressive supranuclear palsy.Supported by NIH Grant No. 2P50 NS 11605-10 |
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Keywords: | Progressive supranuclear palsy Spinal cord Neurofibrillary tangles Neurofilaments Hirano body |
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