中国五省农村人群癫痫流行病学抽样调查

目的：了解中国农村地区癫痫的患病率以及治疗缺口,为开展防治工作提供依据。方法：在黑龙江,宁夏,山西,河南和江苏5个省（区）各选择1个县作为调查点,采用随机整群抽样方法确定调查人群,由经过 统一培训的医生入户调查,每个点样本要求达1万人以上,5省合计调查55 616人,凡初筛调查时确诊或可疑或癫痫者均经神经科医师再次访查确诊。结果：5个调查点共确诊癫痫患者387例,患病率为7．0‰（标化患病率6．8‰）。活动性癫痫患病率为4．6‰,年发病率28．8／10万人口,全部患者中有40．6％未治疗。35．4％的患者治疗不正视,活动性癫痫的治疗缺口高达62．6％,结论：中国农村地区癫痫患病率大大高于以往报道的数字,患者中约有2／3以上没有得到正确的治疗,应尽快制订合理的干预对策。

Epidemiological survey on epilepsy among rural populations in five provinces in China

OBJECTIVE: To investigate the prevalence of epilepsy and its treatment gap in rural areas of China. METHODS: A door-to-door epidemiological survey on epilepsy was conducted among 55616 rural residents in 5 counties, each in a province (Heilongjiang, Ningxia, Shanxi, Henan, and Jiangsu) selected by random cluster sampling. All people diagnosed or suspected as epileptic during the screening phase were rechecked by neurologists. RESULTS: A definite diagnosis of epilepsy was made among 387 people with a prevalence rate 7.0 per thousand (age-adjusted rate 6.8 per thousand). The prevalence of active epilepsy was 4.6 per thousand, and the incidence of epilepsy was 28.8/100 000. Of the people with epilepsy, 40.6% had not been treated, 35.4% were treated irregularly. The treatment gap of active epilepsy was 62.6%. CONCLUSION: The prevalence of epilepsy in the rural areas in China was much higher than it was reported previously. About two thirds of the patients with epilepsy has not received regular treatment. A rational intervention strategy should be developed as soon as possible.