过敏性鼻炎儿童血清维生素D水平的临床研究

目的探讨血清维生素D水平与过敏性鼻炎的相关性。方法选择海珠区妇幼保健院2～6岁儿童100例,其中健康儿童50例为对照组,患过敏性鼻炎儿童50例为实验组,分别使用串联质谱仪检测其血清维生素D水平。结果对照组总维生素D水平为（32.87±4.67）ng/mL,其中维生素D2水平为（3.84±4.21）ng/mL,维生素D3水平为（29.96±2.52）ng/mL;实验组总维生素D水平（23.00±2.00）ng/mL,其中维生素D2水平（3.62±3.04）ng/mL,维生素D3水平（20.38±2.32）ng/mL。两组总维生素D及维生素D3水平比较差异均存在统计学意义（均P〈0.05）。结论过敏性鼻炎儿童血清维生素D水平比正常儿童偏低,且以维生素D3水平偏低为主。

Clinical research on the serum levels of vitamin D in the children with allergic rhinitis

Objective To research the relationship between serum level of vitamin D and allergic rhinitis.Methods 100 children aged from 2 to 6 years old were divided into the experimental group and the control group,each group had 50 cases.Tandem mass spectrometry was used to detect the serum levels of vitamin D.Results Total vitamin D level of control group was(32.87±4.67) ng/mL,vitamin D2 level was(3.84±4.21) ng/mL and vitamin D3 level was(29.96±2.52) ng/mL.Total vitamin D level of experimental group was(23.00±2.00) ng/mL,vitamin D2 level was(3.62±3.04) ng/mL and vitamin D3 level was(20.38±2.32) ng/mL.There were significant differences of total vitamin D level and vitamin D3 level between the two groups(P < 0.05).Conclusion The level of total vitamin D in allergic rhinitis children is lower than that of normal children,with lower level of vitamin D3 primarily.