钙剂、缩宫素、卡孕栓联合纱垫填塞预防高危剖宫产术后出血的效果观察

目的探讨钙剂、缩宫素、卡孕栓联合纱垫填塞在预防高危剖宫产术后出血中的效果。方法选择2009年12月~2011年10月于本院行剖宫产分娩的高危孕妇160例,按随机原则分为研究组和对照组,研究组患者给予钙剂、缩宫素、卡孕栓联合纱垫填塞预防剖宫产后出血,对照组患者给予常规缩宫素预防产后出血,比较两组术中、术后出血量、术后血红蛋白变化情况及新生儿情况。结果两组手术时间差异无统计学意义（P〉0.05）,研究组术中、术后出血量明显少于对照组,差异有统计学意义（P〈0.05）;研究组术后出血率、卡前列素氨丁三醇使用率、血红蛋白下降值明显低于对照组,差异有统计学意义（P〈0.05）;两组术后肛门排气时间、体温恢复时间、住院时间及新生儿窒息情况发生率比较,差异无统计学意义（P〉0.05）;两组产妇均未出现明显的药物不良反应。结论钙剂、缩宫素、卡孕栓联合纱垫填塞预防高危剖宫产术后出血效果良好,且不增加手术时间及副作用,对新生儿无明显影响,值得推广应用。

Effect observation of calcium,Oxytocin,Carprost combined with yarn pad filling on prevention of postpartum hemorrhage of high-risk cesarean section

Objective To investigate the effect of calcium,Oxytocin,Carprost combined with yarn pad filling on prevention of postpartum hemorrhage of high-risk cesarean section.Methods 160 cases of high-risk pregnant women with cesarean section delivery in our hospital from December 2009 to October 2011 were selected and randomly divided into the study group and the control group.Patients in study group were given calcium,Oxytocin,Carprost combined with yarn pad filling treatment to prevent bleeding after cesarean section;patients in the control group were given conventional Oxytocin treatment to prevent postpartum hemorrhage.Intraoperative and postoperative amount of bleeding,postoperative hemoglobin change and neonatal situation of the two groups were compared.Results There was no statistically significant differences in operative time between the two groups(P > 0.05);intraoperative and postoperative amount of bleeding in the study group were less than the control group significantly,the differences were statistically significant(P < 0.05);postoperative bleeding rate,Carboprost Tromethamine usage rate,hemoglobin decreased degree of the study group were lower than those of the control group,the differences were statistically significant(P < 0.05);postoperative anal exhaust time,temperature recovery time,hospital stay and incidence of neonatal asphyxia of the two groups were not significantly differences(P > 0.05);and there was no apparent adverse reaction in the two groups.Conclusion The effect between calcium,Oxytocin,Carprost combined with yarn pad filling on prevention of bleeding after cesarean section is good,without increasing surgical time and side effects,there is no significant effect on the newborns,which should be widely applied.