| Analysis of chromosomes in ascitic fluid cells of ovarian carcinoma |
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| 引用本文： | 王德堂,华钰,张宛明. Analysis of chromosomes in ascitic fluid cells of ovarian carcinoma[J]. 中国人民解放军军医大学学报, 1993, 0(2) |
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| 作者姓名： | 王德堂 华钰 张宛明 |
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| 作者单位： | Department of Obstetrics and Gynecology Xijing Hospital，Fourth Military Medical University，Xi'an 710032，Department of Obstetrics and Gynecology，Xijing Hospital，Fourth Military Medical University，Xi'an 710032，Department of Obstetrics and Gynecology，Xijing Hospital，Fourth Military Medical University，Xi'an 710032 |
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| 摘 要： | Chromosomes in 1620 metaphases of ascitic fluid cells in 20 cases of ovariancarcinoma were analyzed.The results showed that there were marked structuralaberrations aside from significant increase in chromosomal numerical aberrations(85.2%).In the ascitic fluid cells from 12 patients,15 types of marker chromosomes were found,among which t(6;14)(q21;q24)and t(2;6)(q35;p12)were more frequently noted witha rate of 7.84% and 7.59% respectively,which was significantly higher than that of othermarker chromosomes(P<0.01).The findings suggested that,besides t(6;14)(q21;q24),t(2;6)(q35;p12)may also be a specific marker chromosome of ovarian carcinoma.
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Analysis of chromosomes in ascitic fluid cells of ovarian carcinoma |
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| Wang Detang Hua Yu Zhang Wanming. Analysis of chromosomes in ascitic fluid cells of ovarian carcinoma[J]. Journal of Medical Colleges of PLA(China), 1993, 0(2) |
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| Authors: | Wang Detang Hua Yu Zhang Wanming |
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| Affiliation: | Wang Detang Hua Yu Zhang Wanming Department of Obstetrics and Gynecology,Xijing Hospital,Fourth Military Medical University,Xi'an 710032 |
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| Abstract: | Chromosomes in 1620 metaphases of ascitic fluid cells in 20 cases of ovarian carcinoma were analyzed.The results showed that there were marked structural aberrations aside from significant increase in chromosomal numerical aberrations(85.2%). In the ascitic fluid cells from 12 patients,15 types of marker chromosomes were found, among which t(6;14)(q21;q24)and t(2;6)(q35;p12)were more frequently noted with a rate of 7.84% and 7.59% respectively,which was significantly higher than that of other marker chromosomes(P<0.01).The findings suggested that,besides t(6;14)(q21;q24), t(2;6)(q35;p12)may also be a specific marker chromosome of ovarian carcinoma. |
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| Keywords: | ovarian neoplasms ascitic fluid chromosome aberrations marker chromosome |
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