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The production of cerebrospinal fluid in experimental communicating hydrocephalus
Authors:A. Everette James Jr.  G. Novak  A. L. Bahr  B. Burns
Affiliation:(1) Departments of Radiology, The Johns Hopkins Medical Institutions, Baltimore, Md., USA;(2) Departments of Environmental Medicine, The Johns Hopkins Medical Institutions, Baltimore, Md., USA
Abstract:Summary Utilizing an atraumatic model to produce chronic hydrocephalus, CSF production was measured during and after development of communicating hydrocephalus. CSF volume production was significantly lower in animals with increased pressure. Animals with chronic hydrocephalus and normal pressures had abnormal CSF production. Diminished CSF production appears to offer a potential compensatory mechanism when CSF absorption is altered.
Keywords:Communicating hydrocephalus  CSF pressure  Cisternography  Choroid plexus
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