| 山麦冬水溶性提取物对动物实验性心律失常的影响 |
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| 引用本文： | 高广猷,李淑媛,王勖. 山麦冬水溶性提取物对动物实验性心律失常的影响[J]. 大连医科大学学报, 1986, 0(3) |
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| 作者姓名： | 高广猷 李淑媛 王勖 |
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| 作者单位： | 大连医学院药理教研室，大连医学院药理教研室，大连医学院药理教研室 |
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| 摘 要： | 山麦冬水溶性提取物2g/kg iv.可明显缩短肾上腺素致家兔心律失常的持续时间。同样剂量的本品可使乌头碱致大鼠心律失常迅速转复窦性心律。山麦冬水溶性提取物2.5g/kg iv.对氯化钡致大鼠心律失常有明显的对抗作用。本品对哇巴因致豚鼠心律失常及氯化钙致小鼠室颤后的死亡率无明显影响。
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| 关 键 词： | 山麦冬水溶性提取物 心律失常 肾上腺素 乌头碱 哇巴因 |
EFFECTS OF SANMAIDONG WATER SOLUBLE EXTRACT(SWSE)ON EXPERIMENTAL ARRHYTHMIAS IN ANIMALS |
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| Gao Guangyou. EFFECTS OF SANMAIDONG WATER SOLUBLE EXTRACT(SWSE)ON EXPERIMENTAL ARRHYTHMIAS IN ANIMALS[J]. Journal of Dalian Medical University, 1986, 0(3) |
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| Authors: | Gao Guangyou |
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| Affiliation: | Gao Guangyou Department of pharmacology,Dalian Medical College |
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| Abstract: | This paper reported on the experimental results about the antiarrhythmic actions of SWSE on arrhythmic models of animals.The results showed that. (1) SWSE 2g/kg iv prevented obviously the arrhythmia induced by adrenaline in rabbits and the continued time of arrhythmia was shortened obviously by SWSE. (2) The same dose of SWSE,apparently inhibited the arrhythmia induced by aeonitine in rats.It may shorten the time to restore sinus rhythm. (3) SWSE 2.5g/kg iv significantly opposed the arrhythmia induced by BACL_2 in rats.The time to restore sinus rhythm in the SWSE group is shorter than in the control group. (4) SWSE exerted no definite influence on the arrhythmia induced by Ouabain in guinea pigs and the arrhythmia induced by CACL_2 in mice. |
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| Keywords: | Sanmaidong water soluble extract Arrhythmia Adrenaline Aconitine Ouabain |
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