| 赶黄草药理作用及其质量标志物研究进展 |
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| 作者姓名： | 李杰 蒋志涛 刘晓燕 狄留庆 柳春娣 |
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| 作者单位： | 1.南京中医药大学附属张家港医院，药学部，江苏 张家港 215600 |
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| 摘 要： | 赶黄草作为传统苗药，在民间拥有悠久的使用历史。现代药理研究表明赶黄草具有抗氧化、抗肝炎病毒、保护酒精/非酒精性肝损伤和利胆等作用。通过现代分析技术发现赶黄草含有多种化学成分，主要包括类黄酮类、木质素类、香豆素类、苯乙酮类、鞣质类、三萜类等。对赶黄草的活性成分及药理学特性作综述，就其活性成分与药理作用间的联系进行初步探讨，初步确立赶黄草酮B为其质量标志物，为赶黄草的资源开发利用提供参考。
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| 关 键 词： | 赶黄草 药理研究 质量标志物 |
Advances in Pharmacological Effect and Q-marker Research of Penthorum Chinese<\i> |
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| Authors: | LI Jie JIANG Zhi-tao LIU Xiao-yan DI Liu-qing LIU Chun-di |
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| Institution: | 1.Pharmacy Department of Zhangjiagang Hospital Affiliated to Nanjing University of TCM, Zhangjiagang, 215600, China2.School of Pharmacy, Nanjing University of Chinese Medicine, Jiangsu Engineering Research Center for Efficient Delivery System of TCM, Nanjing, 210023, China |
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| Abstract: | As a traditional Miao medicine， Penthorum Chinese has a long history of use in the folk society. Modern pharmacological studies have shown that Penthorum Chinese has antioxidant， anti-hepatitis virus， protection against alcohol/non-alcoholic liver damage and choleretic effects. Through modern analysis techniques， it has been found that the herb contains a variety of chemical components， including flavonoids， lignin， coumarin， acetophenone， tannins and triterpenes. This paper reviews the active ingredients and pharmacological properties of Penthorum Chinese， then studies the relationship between them， and preliminary establish penchinone B as the Q-marker， which provide reference for the resource development and utilization of Penthorum Chinese. |
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| Keywords: | Penthorum Chinese<\i> pharmacological research Q-marker |
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