10例艾滋病合并肺炎患者的临床特点分析

正艾滋病即获得性免疫缺陷综合征(acquired immunodeficiency syndrome,AIDS)是由人免疫缺陷病毒1型(HIV1)和2型(HIV2)所引起~([1]),易发生机会性感染~([2])。本文回顾性分析10例艾滋病合并肺炎患者的病历资料,总结其症状体征、实验室及胸部影像学特征,以提高对该病的诊治水平,减少漏诊、误诊。临床资料承德医学院附属医院呼吸内科2015年10月～2016年6月以肺炎收入院,最后确诊为艾滋病的患

Clinical features of 10 cases of AIDS patients with Pneumonia

Objective:To investigate the clinical characteristic of pneumonia patients combined with AIDS. Methods: Analyse the clinical data of 10 pneumonia patients combined with AIDS from 2015.10 to 2016.6 in respiratory department of the hospital of Chengde Medical College and summarize the clinical symptoms,laboratory tests, chest imaging features, treatment and prognosis. Results:The main symptoms of pneumonia patients combined with AIDS were dyspnea,fatigue and fever. The leukocyte, liver and kidney function in most of the patients was normal,Lactate dehydrogenase (LDH) higher than normal whose means were (1442 ± 491.49) U / L, more than 2 times the upper limit of normal;Most of the severe ones were with low sodium chlorine hypocalcemia. D-dimer was higher whose means were (2.61±0.41) ug/ ml.Fungus-D glucan in 4 patients was high whose means were (99.35 ± 1.51) pg / ml. There were fungus in sputum smear of 6 patients and sputum culture of 4 patients.There were 4 patients who were died with PaO2<60 mmHg. Conclusion:For pneumonia patients with dyspnea, fatigue, nausea and vomiting whose leukocyte was normal,LDH and fungus-D glucan high, and there were fungus in sputum. Patients with low hemoglobin and low sodium chlorine hypocalcemia,whose PaO2 <60 mmHg are with severe illness and high mortality.