Mathematical studies of complement activation |
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| Authors: | M A Garrigue J P Muh P Bardos |
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| Affiliation: | 1. Laboratory for Medical Biochemistry, CNRS, ERA 697, Tours Cédex France;2. Laboratory for Medical Immunology, UER, BP 3223, 37032 Tours Cédex France |
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| Abstract: | Kinetic studies of complement activation were followed by hemolytic assay. Mathematical analysis shows that the curve is composed of two exponents: the first one, which occurs during a short span of time, represents the classical pathway, the second the alternative pathway. We were therefore able to foretell the respective participation of each activator used: inulin, zymosan, and aggregated immunoglobulins. |
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| Keywords: | To whom correspondence should be addressed. |
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