| 熔融法制备碘化钾蜡质骨架缓释片的工艺影响因素考察 |
| |
| 引用本文： | 方平飞,刘晓磊,赵绪元,李焕德,蒋云生. 熔融法制备碘化钾蜡质骨架缓释片的工艺影响因素考察[J]. 中国医院药学杂志, 2011, 0(1) |
| |
| 作者姓名： | 方平飞 刘晓磊 赵绪元 李焕德 蒋云生 |
| |
| 作者单位： | 中南大学湘雅二医院;中南大学药学院; |
| |
| 摘 要： | 目的:系统性考察和优化碘化钾蜡质骨架缓释片的制备工艺。方法:通过单因素考察确定主要影响因素,再进行正交设计优化确定较佳的制备工艺。结果:熔融法制备碘化钾蜡质骨架缓释片最优工艺条件为:加热温度90℃、冷却速度20min,压片时间为制粒后48h。结论:筛选优化的制备工艺稳定可控,重复性好。
|
| 关 键 词： | 熔融法 制备工艺 蜡质 缓释片 |
Investigation on the influence-factor of preparation of potassium iodine wax matrix sustained-release tablets by melting method |
| |
| FANG Ping-fei,LIU Xiao-lei,ZHAO Xu-yuan,LI Huan-de,JIANG Yun-sheng. Investigation on the influence-factor of preparation of potassium iodine wax matrix sustained-release tablets by melting method[J]. Chinese Journal of Hospital Pharmacy, 2011, 0(1) |
| |
| Authors: | FANG Ping-fei LIU Xiao-lei ZHAO Xu-yuan LI Huan-de JIANG Yun-sheng |
| |
| Affiliation: | FANG Ping-fei1,LIU Xiao-lei2,ZHAO Xu-yuan1,LI Huan-de1,JIANG Yun-sheng1(1.Second Xiangya Hospital,Central South University,Hunan Changsha 410011,China,2.School of Pharmaceutical Science,China) |
| |
| Abstract: | |
| |
| Keywords: | melting method preparation technique wax sustained-release tablets |
| 本文献已被 CNKI 等数据库收录！ |
|
