多发性肌炎合并肝脏损害15例临床分析

 目的 总结多发性肌炎(polymyositis,PM)合并肝脏损害患者的临床特点,提高对该病的认识,以利临床诊断、指导治疗及判断预后。方法 从万方数据库上查询国内2000年至2010年发表的PM合并肝脏损害文献共计10篇,选其中资料较完整的14例,以及我科新近收治的2例,共16例,回顾性分析16例PM患者的临床表现、血清肌酶水平以及治疗转归。结果 所有患者均因乏力、转氨酶升高,以“肝病”收入消化内科,首发症状为近端肌无力,血清肌酶对疾病诊断及疗效监测有重要价值,合理应用激素是治疗的关键。结论 PM可引起转氨酶增高,临床症状又类似肝炎,容易误诊。

Clinical Analysis of 15 Patients with Polymyositis Combined with Liver Damage

Objective To summarize the clinical characteristics of polymyositis(PM) combined with liver damage,and thus raise the awareness of this disease and improve the clinical diagnosis,treatment,and prognosis.Methods The clinical characteristics,enzyme levels,and treatment outcome of 15 patients with PM combined with liver damage were analyzed retrospectively.Results Proper application of corticosteroid was important.The patients' condition improved after the administration of corticosteroid,and all the patients ...