| CD11c和NLDC-145单克隆抗体标记的阳性细胞的观察 |
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| 引用本文： | 徐玉东,徐媛媛,刘丽,贾立敏,钟淑琦,魏岚,赵太平,马月秋,伊藤恒敏. CD11c和NLDC-145单克隆抗体标记的阳性细胞的观察[J]. 解剖学报, 2004, 35(4): 409-412 |
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| 作者姓名： | 徐玉东 徐媛媛 刘丽 贾立敏 钟淑琦 魏岚 赵太平 马月秋 伊藤恒敏 |
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| 作者单位： | 哈尔滨医科大学;哈尔滨医科大学;哈尔滨医科大学;哈尔滨医科大学;哈尔滨医科大学;哈尔滨医科大学 |
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| 基金项目： | 黑龙江省科技攻关课题 (G0 0C19190 1) |
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| 摘 要： | 目的 探讨CD11c和NLDC145单克隆抗体标记胸腺内何种间质细胞，并是否具有特异性。方法 应用CD11c单克隆抗体及NLDC-145单克隆进行标记，采用免疫荧光双重染色法及免疫电镜法对胸腺内间质细胞进行观察。结果 CD11c阳性细胞为指状嵌入突起细胞(interdigitating cell，IDC)及少数巨噬细胞。NLDC-145阳性细胞为胸腺上皮细胞。结论 CD11c标记IDC，NLDC-145标记胸腺上皮细胞。胸腺巨噬细胞中存在不同亚群。
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| 关 键 词： | 指状嵌入突起细胞 胸腺上皮细胞 巨噬细胞 CD11c抗体 NLDC-145抗体 小鼠 |
OBSERVATION OF THE POSITIVE CELLS OF THE CD11c AND THE NLDC-145 ANTIBODY MARKER |
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| XU Yu-dong ,XU Yuan-yuan+,LIU Li+,JIA Li-min+,ZHONG Shu-qi+,WEI Lan+,ZHAO Tai-ping+,MA Yue-qiu+,ITOH Tsunetoshi+. OBSERVATION OF THE POSITIVE CELLS OF THE CD11c AND THE NLDC-145 ANTIBODY MARKER[J]. Acta Anatomica Sinica, 2004, 35(4): 409-412 |
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| Authors: | XU Yu-dong XU Yuan-yuan+ LIU Li+ JIA Li-min+ ZHONG Shu-qi+ WEI Lan+ ZHAO Tai-ping+ MA Yue-qiu+ ITOH Tsunetoshi+ |
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| Affiliation: | XU Yu-dong 1*,XU Yuan-yuan+2,LIU Li+1,JIA Li-min+1,ZHONG Shu-qi+2,WEI Lan+1,ZHAO Tai-ping+1,MA Yue-qiu+1,ITOH Tsunetoshi+3 |
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| Abstract: | Objective To study what kind of cells in the thymus can be marked by CD11c and NLDC-145 monoclonal antibody. Methods The experiments were done with CD11c and NLDC-145 monoclonal antibody.Immunofluorescence methods and immunohistochemical electro microscope methods were used in the experiments. Results Interdigitating cells(IDC)were marked by the CD11c antibody.A few of positive cells are macrophages.Two kinds of the macrophages were marked respectively by F4/80 and Mac-2 monoclonal antibodies.The epithelial cells of thymus were marked by the NLDC-145 antibody.Conclusion IDC was marked by the CD11c.Epithelial cells of thymus were marked by the NLDC-145.There are subspecies of macrophage in the thymus. |
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| Keywords: | Interdigitating cell(IDC) Epithelial cell of thymus Macrophage CD11c antibody NLDC-145 antibody Mouse |
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