125例慢性乙肝病毒感染住院患者临床特征分析

目的通过调查分析某院慢性HBV感染住院患者的临床特征,为制定传染病防制对策提供参考依据。方法采用回顾性描述研究的方法,调查患者的一般情况、临床表现、病程、外周血血小板检测结果等。结果慢性乙肝的发病年龄以20~35岁居多,肝硬化和肝癌均在35岁以上;临床表现:慢性乙肝以乏力、纳差为主,肝硬化除乏力纳差外,腹胀明显,肝癌除乏力外,肝区痛较为突出;三者均有不同程度的外周血血小板减少,特别是肝硬化患者血小板减少最为明显。结论慢性HBV感染危害大,应积极推广成年人乙肝疫苗的预防接种;定期作好健康体检,及早诊断,及时治疗,以阻断HBV的持续感染。

Analysis of 125 Patients With Chronic Hepatitis B Virus Infection in a Certain Hospital

Objective To provide measures of preventing infected disease through investigating the clinical characteristics of patients suffering chronic HBV infection. Method The demographic data,clinical features,course of disease and serum platelets counts of these patients were surveyed by reviewing the clinical records.Results Among the patients who suffering HBV infections,chronic hepatitis B,liver cirrhosis and liver neoplasm contributed 60%,17.6% and 22.4% respectively. The high prevalence of chronic hepatitis B was observed predominantly among the young adults between 20 to 35 years old.Patients with cirrhosis and liver cancer were above 35 years old.Males were more than females in all these three kind of patients.Nearly one thirds chronic hepatitis B patients had no obvious clinical presentation.The characteristic manifestations of chronic hepatitis B were fatigue and anorexia,cirrhotic patients with additional significant abdominal distension,and liver cancer patients complained tenderness in the left upper quadrant in addition.Blood platelet counts were decreased in all these three types of patients,particularly among those with cirrhosis. Conclusion It is necessary to prevent hepatitis B virus infection early and extend vaccinations among the adults.