Department of Neuroimmunology, Institute of Neurology, Queen Square, London WC1N 3BG, UK. a.petzold@ion.ucl.ac.uk
Abstract:
Vision in the mesopic range is affected by a number of inherited and acquired clinical disorders. We review these conditions and summarize the historical background, describing the clinical characteristics alongside the genetic basis and molecular biological mechanisms giving rise to rod and cone dysfunction relevant to twilight vision. The current diagnostic gold standards for each disease are discussed and curative and symptomatic treatment strategies are summarized.