新生儿呼吸机相关性肺炎的抗生素治疗

呼吸机相关性肺炎(VAP)检出的致病菌中敏感的抗生素依次为环丙沙星、克林霉素、头孢噻肟,但考虑到新生儿特别是早产儿的生理特点及药物的安全性,头孢噻肟仍为治疗VAP的首选,环丙沙星治疗VAP的疗效好,其软骨及关节损害未被证实,可以选用,克林霉素对新生儿肝功能损害较为严重,建议尽量少用。

Antimicrobil therapy for neonatal ventilator- assoliatsd pneumonia

The disease - causing bactaria found from ventilator - associated pneumonia (VAP) is sensitive to ciprofloxacin. clin-damycin ,cefataxime in tacticity. Think about the pathophysiology and safety of antimicrobil in the particalor prematare infants, cefataxime therapy is the first choice, ciprofloxacin is very effective in neonatal VAP, and it has not been found no evidence on injuring articulation and skeletons, clindamycin injure function of hepar sevevely, we suggest that it shold only be administered when absolutely necessary.